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Updated: Jun 17, 2026

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In vitro Biofilm Formation in an 8-well Chamber Slide
Published on: January 20, 2011
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Formation and Analysis of Biofilms in Vivo
1College of Animal Science and Technology, Henan University of Science and Technology, Luoyang, China.
Methods in Molecular Biology (Clifton, N.J.)
|June 17, 2024
Abstract:
Establishing a biofilm infection model in vivo allows a better understanding of the underlying infection mechanisms of bacteria. Here we describe a method for constructing an in vivo biofilm model of Streptococcus suis. The animal modeled is a piglet, which is the natural reservoir of S. suis, and the mode of clinical infection is simulated by intranasal inoculation of S. suis. This model is in line with clinical practice, easy to operate, and has good repeated stability.

