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Plakophilin 1 in carcinogenesis.

Qiang Luo1, Xiaojia Li1, Keping Xie1,2,3

  • 1Center for Pancreatic Cancer Research, The South China University of Technology School of Medicine, Guangzhou, Guangdong, China.

Molecular Carcinogenesis
|June 18, 2024
PubMed
Summary

Plakophilin 1 (PKP1) is a desmosome protein crucial for skin integrity, with roles beyond cell junctions. Its dysfunction causes ectodermal dysplasia-skin fragility syndrome (EDSF), and it

Keywords:
cancercell connectiondesmosomeinflammationplakophilin 1

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