Related Experiment Video
Updated: Jun 23, 2025

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
Published on: February 1, 2018
A Theoretical Approach to Understand the Nonlinear Processes in Enzymatic Electrochemical Biosensors
Marimuthu Annamalai1, Manimegalai Balu2, Subbiah Alwarappan3
1Department of Mathematics, AMET Deemed to be University, Kanathur, Chennai, Tamilnadu 603112, India.
Abstract:
The enzymatic biosensors' response can be monitored based on the results of nonlinear differential equations. The nonlinear reaction-diffusion equations proposed for this enzyme-based electrochemical biosensor include a nonlinear term associated with Michaelis-Menten kinetics. Herein, the system of nonlinear reaction-diffusion equations is solved using a modified homotopy perturbation method. For all values of the rate constants, the approximate analytical expressions for the concentration profiles, current, sensitivity, and gradient of biosensor have been determined. Performance factors of an enzymatic electrochemical biosensor, such as response time, sensitivity, accuracy, and resistance, are discussed. The analytical results and numerically simulated outcomes using Matlab software have been compared.
More Related Videos
13:15Fabrication of Electrochemical-DNA Biosensors for the Reagentless Detection of Nucleic Acids, Proteins and Small Molecules
Published on: June 1, 2011
13:42Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation
Published on: September 19, 2017
Related Concept Videos
Amperometry: Overview
Introduction to Mechanisms of Enzyme Catalysis
Coulometry: Overview
Interfacial Electrochemical Methods: Overview
Potentiometry: Membrane Electrodes