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Updated: Jun 23, 2025

A Novel Non-invasive Method for the Detection of Elevated Intra-compartmental Pressures of the Leg
Published on: May 31, 2019
Risk factors for acute compartment syndrome in one thousand one hundred and forty seven diaphyseal tibia fractures
Ritchie Strain1,2, Peter Giannoudis3,4
1Academic Department of Trauma & Orthopaedics, School of Medicine, Level D, University of Leeds, Clarendon WingGreat George Street, Leeds, West Yorkshire, LS1 3EX, UK. ritchie.strain1@nhs.net.
Purpose:
Acute compartment syndrome (ACS) remains a devastating complication of orthopaedic trauma. The tibial diaphysis is especially implicated in the development of ACS, both at the time of injury and after operative management. Identification of risk factors for ACS for these distinct scenarios has been investigated in a large cohort of patients.
Methods:
This is a retrospective cohort study of all adults (age 18 years and older) presenting to a level 1 trauma centre with a diaphyseal tibia fracture. ACS was determined by a combination of clinical signs and symptoms and compartmental pressure monitoring. Potential risk factors were subject to univariate analysis with significant variables undergoing binary logistic regression analysis.
Results:
1147 tibial diaphyseal fractures over a twelve year period were studied. Age, multifragmented fracture pattern, male gender, high energy mechanism and intra- articular extension all showed a statistically significant association for ACS. Increasing body mass index (BMI) and treatment with an intramedullary nail favoured development of ACS post-operatively.
Conclusion:
Risk factors for the development of ACS specifically in tibial diaphyseal fractures have been highlighted. Patients managed with IMN or high BMI may warrant particular observation following operative intervention.
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