Related Experiment Videos
Pustulosis palmaris et plantaris: its association with chronic recurrent multifocal osteomyelitis
Journal of the American Academy of Dermatology
|May 1, 1985
Abstract:
Palmoplantar pustules may rarely be associated with chronic recurrent multifocal osteomyelitis in children and young adults. Additional features of this disorder are recurrent low-grade fevers and bone pain. Skeletal radiographs and bone films suggest osteomyelitis, but bone cultures yield no growth of organisms. The cause of this disorder is unknown, and treatment remains unsatisfactory.
Insights
Palmoplantar pustules can rarely indicate chronic recurrent multifocal osteomyelitis (CRMO) in pediatric patients. This bone disorder presents with fever and pain, but cultures are negative, and causes/treatments are unknown.
Area of Science:
- Dermatology and Rheumatology
- Pediatric Osteology
Background:
- Chronic recurrent multifocal osteomyelitis (CRMO) is an idiopathic bone inflammatory condition.
- Palmoplantar pustules are typically associated with skin conditions like psoriasis.
Observation:
- A rare association between palmoplantar pustules and CRMO in children and young adults was noted.
- Patients presented with recurrent low-grade fevers and bone pain.
Findings:
- Radiographic findings suggested osteomyelitis.
- Bone cultures were consistently negative for microbial growth, indicating an aseptic process.
- The etiology of this CRMO presentation remains unknown.
Implications:
- This association expands the differential diagnosis for palmoplantar pustules in pediatric cases.
- Highlights the need for further research into the pathogenesis of CRMO.
- Current treatment strategies for this condition are unsatisfactory, necessitating novel therapeutic approaches.