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Cough in Protracted Bacterial Bronchitis and Bronchiectasis

Hinse Wiltingh1, Julie Maree Marchant1,2, Vikas Goyal1,2,3

  • 1Department of Respiratory and Sleep Medicine, Queensland Children's Hospital, Brisbane, QLD 4101, Australia.

Journal of Clinical Medicine
|June 19, 2024
PubMed

Insights

Protracted bacterial bronchitis (PBB) and bronchiectasis are common causes of chronic cough in children. Cough can be the sole symptom, indicating these conditions and serving as a key treatment outcome.

Area of Science:

  • Pediatric Pulmonology
  • Respiratory Medicine
  • Clinical Pediatrics

Background:

  • Chronic cough is a frequent pediatric complaint with diverse causes.
  • Protracted bacterial bronchitis (PBB) and bronchiectasis represent common and serious etiologies of chronic wet cough in children.
  • Cough is often the primary or only presenting symptom.

Purpose of the Study:

  • To review the significance of cough in pediatric chronic respiratory conditions.
  • To highlight cough as a diagnostic marker for PBB and bronchiectasis.
  • To emphasize cough's role as an outcome measure in treatment and research.

Main Methods:

  • Literature review focusing on pediatric chronic cough.
  • Analysis of studies examining protracted bacterial bronchitis (PBB) and bronchiectasis.
  • Synthesis of evidence on cough as a clinical sign and outcome metric.

Main Results:

  • Protracted bacterial bronchitis (PBB) is a leading cause of chronic wet cough in children.
  • Bronchiectasis represents a more severe end of the chronic wet cough spectrum.
  • Cough is a critical indicator for diagnosing PBB and bronchiectasis.

Conclusions:

  • Cough is a vital sign for identifying pediatric protracted bacterial bronchitis (PBB) and bronchiectasis.
  • The resolution of cough is a crucial endpoint for evaluating treatment efficacy.
  • Further research should leverage cough as a primary outcome measure.

Keywords:
bronchiectasischildrencoughprotracted bacterial bronchitisreview

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