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Updated: Jun 23, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Radical Cyclization-Initiated Difunctionalization Reactions of Alkenes and Alkynes
Sanjun Zhi1, Xiaoming Ma2, Wei Zhang3
1Jiangsu Key Laboratory for the Chemistry of Low-Dimensional Materials, Huaiyin Normal University, 111 Changjiang West Road, Huaian 223300, China.
Abstract:
Radical reactions are powerful in the synthesis of diverse molecular scaffolds bearing functional groups. In previous review articles, we have presented 1,2-difunctionalizations, remote 1,3-, 1,4-, 1,5-, 1,6- and 1,7-difunctionalizations, and addition followed by cyclization reactions. Presented in this paper is radical cyclization followed by the second functionalization reaction. The second functionalization could be realized by atom transfer reactions, radical or transition metal-assisted coupling reactions, and reactions with neutral molecules, cationic and anionic species.
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