2D Materials in Advanced Electronic Biosensors for Point-of-Care Devices.
Sobia Nisar1,2, Ghulam Dastgeer3, Zafar Muhammad Shazad4,5
1Department of Electrical Engineering, Sejong University, Seoul, 05006, Republic of Korea.
Two-dimensional (2D) materials are revolutionizing point-of-care (PoC) diagnostics with field-effect transistor biosensors (bio-FETs). These advanced bio-FETs offer sensitive, real-time, label-free detection for diverse biomedical applications.
Area of Science:
- Materials Science
- Biotechnology
- Nanoscience
Background:
- Two-dimensional (2D) materials possess unique properties driving innovation in technology.
- 2D-based field-effect transistor biosensors (bio-FETs) show significant promise for point-of-care (PoC) biomedical diagnostics.
Purpose of the Study:
- This review details the mechanisms and capabilities of 2D material-based bio-FETs.
- It explores applications, advantages, limitations, and future prospects of these biosensors.
Main Methods:
- The review synthesizes information on graphene, transition metal dichalcogenides (TMDCs), and black phosphorus in bio-FETs.
- It includes a comparative analysis of different biosensing platforms.
Main Results:
- 2D material-based bio-FETs enable low detection limits (LOD), real-time, label-free, and selective diagnostics.
- Applications span from conventional to wearable biomedical devices.
Conclusions:
- 2D material-based bio-FETs offer substantial advantages for advanced biomedical diagnostics.
- Further research is encouraged to overcome challenges and advance the field.
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