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Radiofrequency ablation compared to surgery for thyroid nodules: A case for office based treatment
Alex K F Lee1, Thomas Hui1, Zenon W C Yeung1
1Department of Otorhinolaryngology, Head and Neck Surgery Tseung Kwan O Hospital Hong Kong Hong Kong.
Laryngoscope Investigative Otolaryngology
|June 19, 2024
Summary
Radiofrequency ablation (RFA) is a safe and effective treatment for benign thyroid nodules, offering reduced procedure time, fewer complications, and lower costs compared to hemithyroidectomy. This scarless, local anesthetic procedure is a valuable alternative, especially in resource-limited settings.
Area of Science:
- Otolaryngology
- Endocrinology
- Minimally Invasive Surgery
Background:
- Benign thyroid nodules can cause significant symptoms, necessitating effective treatment options.
- Conventional hemithyroidectomy, while effective, involves surgery with associated risks and longer recovery.
- Exploring less invasive and more cost-effective alternatives is crucial, particularly in public healthcare systems.
Purpose of the Study:
- To evaluate the safety and effectiveness of radiofrequency ablation (RFA) for benign thyroid nodules performed by ENT surgeons.
- To compare RFA with conventional hemithyroidectomy in a public healthcare setting.
Main Methods:
- A study of 50 patients undergoing RFA for symptomatic benign thyroid nodules was conducted between 2020-2022.
- Objective outcomes included nodule volume reduction rate (VRR) and complications.
- Subjective patient-reported outcomes assessed symptoms (obstructive, cosmetic, pain) and satisfaction.
Main Results:
- Significant reductions in mean nodule volume (VRR) and symptom scores (obstructive, cosmetic) were observed at 3, 6, and 12 months post-RFA.
- Radiofrequency ablation demonstrated a shorter mean procedure time and a lower complication rate compared to hemithyroidectomy.
- The estimated patient cost for RFA was less than half that of hemithyroidectomy.
Conclusions:
- Radiofrequency ablation is a safe and effective treatment for benign thyroid nodules, offering a scarless, local anesthetic procedure.
- RFA presents advantages over hemithyroidectomy, including shorter procedure time, reduced complications, and lower patient cost.
- RFA serves as a valuable alternative to hemithyroidectomy, particularly in resource-limited public healthcare settings with long waiting times.

