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MAME Models for 4D Live-cell Imaging of Tumor: Microenvironment Interactions that Impact Malignant Progression
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Editorial: Modelling and sensing platform for cancer and tumour microenvironment
Yuji Nashimoto1, Yusuke Kanno2, Hidenori Ito3
1Institute of Biomaterials and Bioengineering (IBB), Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Frontiers in Bioengineering and Biotechnology
|June 19, 2024
Summary
No abstract available in PubMed .
Keywords:
biosensorscancer stem cell (CSC)microfluidic devicemicrophysiological system (MPS)organ-on-a-chip (OOC)tissue engineeringtumor microenevironmenttumor modelMore Related Videos
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The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...
The Tumor Microenvironment
Every normal cell or tissue is embedded in a complex local environment called stroma, consisting of different cell types, a basal membrane, and blood vessels. As normal cells mutate and develop into cancer cells, their local environment also changes to allow cancer progression. The tumor microenvironment (TME) consists of a complex cellular matrix of stromal cells and the developing tumor. The cross-talk between cancer cells and surrounding stromal cells is critical to disrupt normal tissue...