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Updated: Jun 23, 2025

Adapted Resistance Training Improves Strength in Eight Weeks in Individuals with Multiple Sclerosis

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Published on: January 29, 2016

Personalized Intervention to Improve Medication Adherence for Persons with Multiple Sclerosis.

Efrat Neter¹, Efrat Esterkin-Hubner², Lea Glass-Marmor²

¹Ruppin Academic Center, Emeq Hefer, Israel.

Patient Preference and Adherence

|June 19, 2024

Summary

This study found that a combined psycho-education and Motivational Interviewing (MI) intervention initially improved medication adherence for persons with relapsing-remitting multiple sclerosis (PwRRMS). However, the gains were not sustained long-term, suggesting a need for ongoing support.

Keywords:

disease modifying therapy medication adherence medication beliefs motivational interviewing multiple sclerosis participatory medicine patient reported outcomes

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A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

Area of Science:

Neuroscience
Psychology
Public Health

Background:

Relapsing-remitting multiple sclerosis (RRMS) requires consistent Disease Modifying Treatment (DMT) adherence for optimal management.
Non-adherence to DMT in RRMS can lead to disease progression and increased healthcare costs.
Psycho-education and Motivational Interviewing (MI) are potential strategies to improve medication adherence.

Purpose of the Study:

To assess the acceptability, retention, and efficacy of a combined face-to-face psycho-education and MI intervention for improving DMT adherence in persons with RRMS (PwRRMS).
To evaluate the impact of the intervention on self-reported medication adherence over a 12-month period.

Main Methods:

A quasi-experimental pre-test post-test design was used with 60 PwRRMS identified as non-adherent to their DMT.
Participants received a combination of physician counseling, tailored MI sessions, a telephone booster, and a follow-up MI session.
Patient-reported outcomes, including adherence scores, were collected at baseline, 6 months, and 12 months.

Main Results:

Retention rates were reasonable, with 52 out of 60 participants completing the intervention and 46 completing the 12-month follow-up.
Adherence scores significantly improved at the 6-month mark compared to baseline (p = 0.030).
However, adherence scores at 12 months were not significantly different from baseline (p = 0.106), indicating a lack of sustained effect.

Conclusions:

The combined psycho-education and MI protocol demonstrated initial efficacy in enhancing medication adherence for PwRRMS.
The study highlights the need for sustained or more frequent interventions to maintain long-term adherence improvements.
Further research should explore strategies for long-term adherence support in chronic disease management.