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Pancreatic masses clinically diagnosed as tuberculosis: Case reports
Vernon Chuabio1, Johanna Bandoy1, Aaron Ong1
1Division of Gastroenterology, Department of Medicine, University of the Philippines-Philippine General Hospital, Manila, Philippines.
SAGE Open Medical Case Reports
|June 19, 2024
Summary
Pancreatic masses can be benign, like tuberculosis, avoiding unnecessary surgery. Empiric anti-tuberculosis treatment resolved masses in three patients, supporting less invasive options.
Area of Science:
- Gastroenterology and Hepatology
- Infectious Diseases
- Oncology
Background:
- Pancreatic masses are frequently detected, often raising concerns for malignancy.
- Surgical intervention is common but can be excessive for benign conditions.
- Exploring less invasive diagnostic and therapeutic avenues for potentially benign pancreatic masses is crucial.
Observation:
- Three adult Filipino patients presented with symptomatic pancreatic masses mimicking cancer on imaging.
- Two patients were smokers with no prior tuberculosis history.
- All patients received empiric anti-tuberculosis treatment due to co-existing extrapancreatic tuberculosis.
Findings:
- Resolution of pancreatic masses was confirmed via endoscopic ultrasound post-treatment in all three cases.
- This suggests tuberculosis as a treatable cause of pancreatic masses.
- Empiric treatment proved effective in resolving the pancreatic lesions.
Implications:
- In tuberculosis-endemic areas, pancreatic tuberculosis should be considered in the differential diagnosis of pancreatic masses.
- Less invasive approaches, including empiric treatment when tissue sampling is not feasible, may be warranted.
- This approach can help prevent unnecessary surgeries for benign pancreatic conditions.
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