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Dose-Response Relationship Between Perceived Control and Depression in Patients With Chronic Heart Failure: A

Yaqi Wang, Xueying Xu, Qingyun Lv

    The Journal of Cardiovascular Nursing
    |June 19, 2024
    PubMed

    Insights

    Increasing perceived control significantly lowers depression risk in chronic heart failure (CHF) patients. Interventions are crucial, especially before a key control threshold is reached.

    Area of Science:

    • Cardiology
    • Psychiatry
    • Health Psychology

    Background:

    • The relationship between perceived control and depression in chronic heart failure (CHF) patients is not well understood.
    • A dose-response relationship between perceived control and depression in CHF is largely unknown.

    Purpose of the Study:

    • To investigate the linear and nonlinear relationship between perceived control and depression in CHF patients.
    • To explore potential subgroup differences in this relationship.

    Main Methods:

    • 308 patients with CHF were analyzed.
    • Data included perceived control, depression, gender, age, NYHA classification, and comorbidity burden.
    • Statistical analyses included logistic regression, Spearman correlation, and restricted cubic spline analysis.

    Main Results:

    • Higher perceived control quartiles were associated with lower depression risk (ORs 0.29-0.20).
    • A significant negative correlation was found between perceived control and depression (r = -0.317, P < .01).
    • An "L-shaped" nonlinear relationship was observed, with depression risk rapidly decreasing until a control score of 20, after which it stabilized.

    Conclusions:

    • Enhancing perceived control may reduce depression risk in CHF patients.
    • Interventions should focus on patients below the identified control threshold of 20.
    Abstract

    Keywords:
    chronic heart failuredepressiondose-response relationshipperceived control

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