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Feasibility and Acceptability Evaluation of a Digital Therapeutic Program for Improving Cancer Prevention: A
Xianwei Zhang1, Sheng Zhang1, Haiyan Zhang1
1Key Laboratory of Biorheological Science and Technology of Ministry of Education, College of Bioengineering, Chongqing University, No. 174 Shazheng Road, Shapingba District, Chongqing, 400044, China.
Abstract:
Previous studies have proved that healthy behaviors hinder the onset and progression of tumors. Digital therapeutics (DTx), playing a pivotal role in facilitating behavioral adjustments through educational interventions, lifestyle support, and symptom monitoring, contribute to the goal of tumor prevention. We aim to optimize the evaluation of the feasibility and acceptability of DTx for cancer prevention. This involves assessing AITI's daily activity rates and user feedback, and comparing changes in behavioral habits and differences in SF-36 before and after the intervention. In a 4-week trial with 57 participants engaging actively, we found both the average daily activity rate and 4-week retention rate at 35 (61.4%). The USE Questionnaire scores (validity, ease of use, acquisition, and satisfaction) ranged from 68.06 to 83.10, indicating AITI's user-friendliness and acceptability. Furthermore, positive habit changes were noted among participants in exercise and diet (p < 0.0001), suggesting the effectiveness of the DTx approach in modifying behavioral habits related to physical activity and nutrition. This pilot study underscores the potential of DTx in advancing cancer prevention. However, larger and longer studies are needed to comprehensively assess its impact.
Insights
Digital therapeutics (DTx) show promise for cancer prevention by encouraging healthy habits. A pilot study found DTx interventions led to significant improvements in exercise and diet, demonstrating their feasibility and acceptability.
Area of Science:
- Oncology
- Digital Health
- Behavioral Science
Background:
- Healthy behaviors are crucial for hindering tumor onset and progression.
- Digital therapeutics (DTx) facilitate behavioral adjustments for cancer prevention through education, lifestyle support, and monitoring.
Purpose of the Study:
- To evaluate the feasibility and acceptability of a digital therapeutic (DTx) for cancer prevention.
- To assess daily activity rates, user feedback, behavioral habit changes, and quality of life (SF-36) post-intervention.
Main Methods:
- A 4-week pilot trial involving 57 active participants.
- Assessed daily activity rates, 4-week retention rates, and user feedback via the USE Questionnaire.
- Compared changes in exercise and diet habits and SF-36 scores before and after the DTx intervention.
Main Results:
- Achieved a 61.4% 4-week retention rate.
- USE Questionnaire scores indicated high user-friendliness and acceptability (68.06–83.10).
- Significant positive changes in exercise and diet habits were observed (p < 0.0001).
Conclusions:
- This pilot study highlights the potential of DTx in cancer prevention.
- DTx interventions are feasible and acceptable for promoting healthy behaviors.
- Larger, longer studies are warranted to confirm the long-term impact of DTx on cancer prevention.
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