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Updated: Jul 12, 2026
Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing
Published on: June 1, 2012
Advances in microneedles for transdermal diagnostics and sensing applications
Lei Wang1, Yingli Wang1, Xiao Wu1
1Key Laboratory of Optic-electric Sensing and Analytical Chemistry for Life Science, Shandong Key Laboratory of Biochemical Analysis, Key Laboratory of Analytical Chemistry for Life Science in Universities of Shandong, College of Chemistry and Molecular Engineering, MOE, Qingdao University of Science and Technology, Qingdao, 266042, China.
Microneedles offer minimally invasive ways to create personalized diagnostic devices for use at the point-of-care (POC). This review covers advances in microneedle sensors for transdermal diagnostics and wearable technology.
Area of Science:
- Biomedical Engineering
- Nanotechnology
- Diagnostics
Background:
- Microneedles enable minimally invasive transdermal sensing for personalized diagnostics.
- Wearable technologies integrate microneedle systems for user-friendly biochemical detection and physiological monitoring.
Purpose of the Study:
- To provide a comprehensive overview of microneedle-based sensor devices for transdermal diagnostics.
- To critically analyze the state-of-the-art in microneedle technology and its practical applications.
Main Methods:
- Review of current literature on microneedle sensor devices.
- Emphasis on biological basis, fabrication, and applications of microneedles.
- Summary of various sensing strategies employed in microneedle devices.
Main Results:
- Microneedle technology is advancing rapidly for point-of-care diagnostic platforms.
- Integration with wearable tech enhances user-friendliness for biochemical and physiological monitoring.
- Diverse sensing strategies are being developed for microneedle applications.
Conclusions:
- Microneedle-based transdermal diagnostics show significant potential for personalized healthcare.
- Challenges remain in bridging technology development with real-world applications.
- Future prospects include further integration and refinement of microneedle sensing systems.
