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Updated: Jun 23, 2025

Partial Lobular Hepatectomy: A Surgical Model for Morphologic Liver Regeneration
Published on: May 31, 2018
Polysubstance-Induced Hepatotoxicity and the Role of Supportive Management
Nadim A Qadir1, Luke Stachler1, Anvit D Reddy1
1Internal Medicine, University of Florida College of Medicine - Jacksonville, Jacksonville, USA.
Abstract:
With the continued rise of polysubstance use throughout the country, it has been shown to affect a multitude of organ systems. Drug-induced liver injury (DILI) has been widely documented in its association with salicylates or acetaminophen and the utility of using N-acetylcysteine (NAC) for its hepatoprotective effects. However, DILI caused by illicit drug use and guideline-directed management has had little research. We present the case of a 29-year-old female who presented with altered mental status. She was found to have a concomitant liver injury and was treated supportively without the use of NAC, with gradual improvement.
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