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Updated: Jun 23, 2025

A Patient-Derived Xenograft Model for Venous Malformation

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Giant vascular malformations invading the skull: A case report.

Ming-Chen Xie¹, Fu-Xu Wang¹, Jian Xu²

¹Department of Neurosurgery, The Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China.

World Journal of Clinical Cases

|June 20, 2024

Summary

Giant vascular malformations (VMs) in the head and face are rare. Surgical removal is complex, requiring extensive preparation to manage risks and ensure patient recovery, as demonstrated in a pediatric case.

Area of Science:

Vascular Surgery
Pediatric Neurosurgery
Medical Imaging

Background:

Vascular malformations (VMs) result from errors in angiogenesis, often congenital but not always apparent at birth.

Keywords:

Case report Early intervention Giant vascular malformation Interventional embolization Surgical intervention

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Giant VMs of the head and face are rare, with limited data on surgical outcomes.

The prognosis for surgical intervention in such cases remains unclear.