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Suk Bae Seo1, Jovian Wan2, Lisa Kwin Wah Chan3

  • 1SeoAhSong Dermatologic Clinic, Seoul, South Korea.

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [And] International Society for Digital Imaging of Skin (ISDIS) [And] International Society for Skin Imaging (ISSI)
|June 20, 2024
PubMed
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Laser-assisted needle-free microjet injection of poly-d,l-lactic acid effectively treated atrophic scars, showing high patient satisfaction and improved skin texture. Mild, transient side effects were noted, with no adverse events observed.

Area of Science:

  • Dermatology
  • Aesthetic Medicine
  • Regenerative Medicine

Context:

  • Atrophic acne scars significantly impact quality of life and present treatment challenges.
  • Poly-d,l-lactic acid is a known collagen stimulator for scar treatment.
  • Novel delivery systems are being explored to enhance treatment efficacy and patient experience.

Purpose:

  • To evaluate the efficacy and safety of poly-d,l-lactic acid administered via laser-assisted needle-free microjet injection for atrophic scar treatment.
  • To assess patient satisfaction and clinical improvement following the procedure.

Summary:

  • A study involving five participants with atrophic facial scars utilized the Mirajet system for poly-d,l-lactic acid delivery over five sessions.
  • Clinical assessments at 12 and 22 weeks showed significant improvements in scar appearance and skin texture, with high patient satisfaction.
Keywords:
acne scaracne vulgarisl‐lactic acidneedle‐free injectorpoly‐dscar

Related Experiment Videos

  • The treatment was well-tolerated, reporting only mild, temporary discomfort and no adverse events.

    • Impact:

    • This novel needle-free delivery method shows promise for effectively treating atrophic scars.
    • Results suggest a potential for improved patient outcomes and satisfaction in acne scar management.
    • Further investigation via randomized controlled trials is recommended to confirm long-term efficacy and safety.