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Updated: Jun 18, 2026

Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Left ventricular ejection fraction: time to revise the metric?
Avik Ray1, Dan Zlotoff2, Ichiro Kawachi3
1Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02120, United States.
Patients often misunderstand normal left ventricular ejection fraction (LVEF) values due to proportion bias. A new LVEF-Proportion of Normal metric aims to improve patient understanding and adherence for better cardiac outcomes.
Area of Science:
- Cardiology
- Medical Education
- Health Psychology
Background:
- Patients frequently misunderstand normal left ventricular ejection fraction (LVEF) values.
- This misunderstanding stems from the proportion dominance effect, leading to misinterpretation of cardiac function.
- Misconceptions about LVEF negatively impact patient morale, adherence, and clinical outcomes.
Purpose of the Study:
- To identify and explain the common patient misconception regarding normal left ventricular ejection fraction.
- To introduce a novel metric, "Left Ventricular Ejection Fraction - Proportion of Normal" (LVEF-PN).
- To assess the potential of LVEF-PN in improving patient comprehension, engagement, and adherence.
Main Methods:
- Analysis of the psychological phenomenon of proportion dominance effect in patient interpretation of LVEF.
- Development of the LVEF-PN metric, adjusting LVEF to a patient-specific normal range.
- Conceptual framework for utilizing LVEF-PN to enhance patient-provider communication.
Main Results:
- The proportion dominance effect significantly contributes to patient misinterpretation of LVEF values.
- The proposed LVEF-PN metric offers a patient-centric approach to understanding cardiac function.
- This approach has the potential to improve patient comprehension and adherence.
Conclusions:
- Patient misunderstanding of normal LVEF is a significant barrier to effective cardiac care.
- The LVEF-Proportion of Normal metric provides a more intuitive and accurate way for patients to grasp their cardiac status.
- Implementing LVEF-PN may lead to improved patient adherence and better clinical outcomes in cardiovascular medicine.
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