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Antibiotic bone cement accelerates diabetic foot wound healing-Elucidating the role of ROCK1 protein expression

Liang Li1, Guangming Zhang2, Yanwei Sun1

  • 1Department of Burns & Plastic Surgery, Zibo Central Hospital, Zibo, People's Republic of China.

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PubMed
Abstract

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Diabetic Foot Ulcer01:31

Diabetic Foot Ulcer

Definition A diabetic foot ulcer (DFU) is a chronic, non-healing wound that develops in individuals with diabetes. It typically occurs on pressure-bearing areas such as the heel, metatarsal heads, or hallux, and carries a high risk of infection and amputation.Pathophysiology • The development of DFUs can be explained by four interconnected mechanisms: neuropathy, ischemia, infection, and impaired wound healing. • Neuropathy is the most common factor. Sensory neuropathy reduces pain perception,...

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