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Updated: Jun 23, 2025

Ultrasonic-Assisted Extraction of Cannabidiolic Acid from Cannabis Biomass
Published on: May 27, 2022
Advancement of Research Progress on Synthesis Mechanism of Cannabidiol (CBD)
Fu Wang1, Zhenyuan Zang1, Qian Zhao1
1Faculty of Agronomy, Jilin Agricultural University, Changchun 130118, China.
Abstract:
Cannabis sativa L. is a multipurpose crop with high value for food, textiles, and other industries. Its secondary metabolites, including cannabidiol (CBD), have potential for broad application in medicine. With the CBD market expanding, traditional production may not be sufficient. Here we review the potential for the production of CBD using biotechnology. We describe the chemical and biological synthesis of cannabinoids, the associated enzymes, and the application of metabolic engineering, synthetic biology, and heterologous expression to increasing production of CBD.
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