Related Experiment Video

Updated: Aug 19, 2026

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents
10:53

Isolation of Human Atrial Myocytes for Simultaneous Measurements of Ca2+ Transients and Membrane Currents

Published on: July 3, 2013

Tiapamil--a new calcium antagonist

L H Opie, C A Muller, F T Thandroyen

    South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde
    |June 1, 1985
    PubMed

    Insights

    Tiapamil, a new calcium antagonist, shows promise for treating heart rhythm disorders and acute myocardial infarction. Further clinical studies are recommended to establish its therapeutic value alongside existing treatments.

    Area of Science:

    • Cardiovascular pharmacology
    • Clinical electrocardiology

    Background:

    • Calcium antagonists represent a significant advancement in cardiovascular medicine.
    • Tiapamil, a verapamil congener, is under investigation for its therapeutic potential.

    Purpose of the Study:

    • To evaluate the anti-arrhythmic effects of tiapamil.
    • To assess the intravenous use of tiapamil in acute myocardial infarction patients.

    Main Methods:

    • Experimental studies on anti-arrhythmic properties.
    • Clinical evaluation in patients with acute myocardial infarction.

    Main Results:

    • Preliminary experimental data suggest anti-arrhythmic properties.
    • Intravenous administration in acute myocardial infarction warrants further investigation.

    Conclusions:

    • Tiapamil demonstrates potential as a novel cardiovascular therapeutic agent.
    • Further clinical evaluation is necessary to confirm its role in established calcium antagonist therapy.

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