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Beta cell dedifferentiation in type 1 diabetes: sacrificing function for survival?

Kierstin L Webster1, Raghavendra G Mirmira1

  • 1Kovler Diabetes Center and the Department of Medicine, The University of Chicago, Chicago, IL, United States.

Frontiers in Endocrinology
|June 21, 2024
PubMed
Summary

Beta cell dedifferentiation, a key factor in type 1 diabetes pathogenesis, offers a novel therapeutic target. Understanding these mechanisms could lead to interventions that restore beta cell function and reduce autoimmunity.

Keywords:
autoimmunitybeta celldedifferentiationislettype 1 diabetes

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