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An unusual outbreak of parvovirus B19 infections, France, 2023 to 2024

Camille d'Humières1,2, Anne Fouillet1,3, Laura Verdurme2

  • 1These authors contributed equally to this work and share first authorship.

Euro Surveillance : Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin
|June 21, 2024
PubMed

Insights

France experienced an unprecedented parvovirus B19 epidemic from April 2023 to May 2024, with a fourfold increase in infections. This surge impacted children

Area of Science:

  • Virology
  • Epidemiology
  • Public Health

Background:

  • Parvovirus B19 (B19V) is a common human virus.
  • Previous B19V epidemics have been documented, notably in 2019.
  • Understanding current epidemic trends is crucial for public health preparedness.

Purpose of the Study:

  • To report and analyze the unusual parvovirus B19 epidemic in France between April 2023 and May 2024.
  • To compare the scale of this epidemic to previous B19V outbreaks.
  • To highlight the clinical and epidemiological impact of the current B19V surge.

Main Methods:

  • Analysis of B19V IgM-positive serology data from April 2023 to May 2024.
  • Corroboration of serological findings with clinical data from emergency networks.
  • Assessment of morbidity and mortality consequences in different age groups.

Main Results:

  • A fourfold increase in B19V IgM-positive serologies compared to the 2019 epidemic.
  • Clinical data confirmed a significant rise in B19V infections.
  • Morbidity and mortality impacts were evident in children, while adult increases were primarily seen in laboratory data.

Conclusions:

  • The period from April 2023 to May 2024 marked an unusual and significant parvovirus B19 epidemic in France.
  • Children were disproportionately affected by the morbidity and mortality consequences of this epidemic.
  • Healthcare professionals and policymakers need to be informed to improve prevention, diagnosis, and management of at-risk patients during B19V outbreaks.
Keywords:
FranceParvovirus B19laboratory surveillancemortalityoutbreaksyndromic surveillance

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