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Highly selective fluorescence turn-on sensor for·thiol compounds detection.

Chaowei Zhang1, Dandan Wang1, Yiduo Chen1

  • 1Key Laboratory of Advanced Materials of Tropical Island Resources, Ministry of Education, School of Chemistry and Chemical Engineering, Hainan University, Haikou 570228, China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|June 21, 2024
PubMed
Summary
This summary is machine-generated.

A new fluorescent probe (Cu@Zn-CP) offers sensitive detection of harmful thiol compounds. This recyclable sensor provides rapid, accurate results in environmental samples, ensuring safety.

Keywords:
CPsFluorescence sensorFunctionalizationThiol compoundsTurn-on

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Area of Science:

  • Environmental Chemistry
  • Materials Science
  • Analytical Chemistry

Background:

  • Thiol compounds are prevalent in pesticides and pose significant environmental and human health risks upon release.
  • Efficient and sensitive detection methods for thiol compounds are crucial for environmental monitoring and safety.

Purpose of the Study:

  • To develop a highly sensitive, turn-on fluorescent probe for detecting thiol compounds.
  • To create a recyclable sensor with rapid response times and broad applicability.

Main Methods:

  • Fabrication of a zinc coordination polymer (Zn-CP) doped with Cu2+ ions to create a quenched fluorescent probe (Cu@Zn-CP).
  • Evaluation of the probe's response to methyl thioglycolate (MTC), including detection limit, response time, and recyclability.
  • Testing the probe's efficacy in detecting MTC in real environmental samples (river water) and various other thiol compounds.

Main Results:

  • The Cu@Zn-CP probe exhibited a rapid (90 s) turn-on fluorescence response to MTC with a low detection limit of 23 ppb.
  • The sensor demonstrated excellent recyclability over five cycles and maintained high detection performance.
  • Successful detection of MTC in river water with a spike recovery rate of 98-103%, and broad applicability to diverse thiol compounds.

Conclusions:

  • The developed Cu@Zn-CP probe is a highly sensitive and recyclable fluorescent sensor for thiol compounds.
  • This sensor shows great potential for real-time environmental monitoring and ensuring the safety of synthetic materials.
  • The probe's universality for various thiols highlights its significance in analytical chemistry and environmental safety.