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Post-stroke urinary incontinence is associated with behavior control deficits and overactive bladder.
Michitaka Funayama1, Akihiro Koreki2, Taketo Takata3
1Department of Neuropsychiatry, Ashikaga Red Cross Hospital, Ashikaga, Tochigi, 326-0843, Japan; Department of Rehabilitation, Edogawa Hospital, Edogawa, Tokyo, 133-0052, Japan; Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, 160-0016, Japan.
Neuropsychologia
|June 21, 2024
Summary
Urinary incontinence after stroke is linked to overactive bladder and behavioral control issues. Lesion mapping suggests ventromedial prefrontal cortex damage may play a role.
Area of Science:
- Neuroscience
- Urology
- Gerontology
Background:
- Urinary incontinence significantly impacts stroke survivors' quality of life.
- Neuropsychological mechanisms and neural basis of post-stroke urinary incontinence are under-investigated.
Purpose of the Study:
- Investigate the neuropsychological mechanisms and neural substrates of urinary incontinence in stroke survivors.
- Determine the relationship between urinary incontinence and cognitive/behavioral deficits.
Main Methods:
- Cross-sectional study of 71 individuals with cerebrovascular disease.
- Neuropsychological assessment and neuroimaging (MRI) including voxel-based lesion-behavior mapping.
- Statistical analyses including linear regression and Mann-Whitney U test.
Main Results:
- Behavioral control deficits and overactive bladder severity correlate with urinary incontinence severity.
- Voxel-based lesion-behavior mapping indicated a potential association between ventromedial prefrontal cortex lesions and urinary incontinence severity, though not statistically significant.
Conclusions:
- Post-stroke urinary incontinence is associated with neurogenic overactive bladder and cognitive dysfunction (behavioral control deficits).
- Findings highlight the complex interplay between neurological damage, cognitive function, and bladder control in stroke survivors.
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