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Related Experiment Videos

Occupational asthma caused by sewer flies.

B L Gold, K P Mathews, H A Burge

    The American Review of Respiratory Disease
    |June 1, 1985
    PubMed
    Summary

    Occupational asthma can be triggered by insect emanations. This study identifies sewer flies (Psychoda alternata) as a cause of allergic asthma in a sewage plant worker, with limited cross-reactivity to other insects.

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    Area of Science:

    • * Allergy and Immunology
    • * Environmental Health
    • * Occupational Medicine

    Background:

    • * Insect emanations are recognized triggers for allergic asthma, particularly in occupational settings.
    • * Previous sensitization to one insect allergen may predispose individuals to others.

    Observation:

    • * A sewage plant worker developed asthma linked to exposure to sewer flies (Psychoda alternata).
    • * The patient had a history of immediate-type hypersensitivity to wax moths.

    Findings:

    • * Diagnostic evidence included skin tests, Prausnitz-Kustner testing, leukocyte histamine release, ELISA, and bronchial challenge.
    • * ELISA inhibition showed minimal cross-reactivity between sewer fly and wax moth extracts.
    • * Skin testing suggested potential hypersensitivity to other Diptera families.

    Implications:

    • * Highlights sewer flies as a specific occupational asthma hazard.
    • * Suggests the need for targeted allergen testing in individuals with occupational asthma.
    • * Indicates potential for cross-reactivity within the order Diptera, warranting further investigation.

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