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Enterococcus-related vascular graft infection: A case series
Jules Bauer1, Olivier Robineau2, Jonathan Sobocinski3
1Service Universitaire des Maladies Infectieuses et du Voyageur, CH Dron, 59200 Tourcoing, France.
Infectious Diseases Now
|June 21, 2024
Summary
Enterococcal vascular graft infections, often polymicrobial, occur early post-surgery and impact patients with comorbidities. Management involves antibiotics, with significant mortality and relapse rates observed.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Microbiology
Background:
- Vascular graft infections pose significant challenges in patient management.
- Enterococcal species are increasingly recognized as pathogens in healthcare-associated infections.
Purpose of the Study:
- To determine the incidence, clinical characteristics, and outcomes of enterococcal-related vascular graft infections.
- To analyze the management strategies and associated burdens of these infections.
Main Methods:
- A prospective cohort study was conducted from 2008 to 2021.
- Data on vascular graft infections managed at a referral center were collected.
- Infection history, management, prosthesis type, and outcomes were analyzed.
Main Results:
- Enterococcal vascular graft infections accounted for 12% of cases (29/249).
- Most infections were early-onset (76%) and polymicrobial (90%), frequently involving Enterobacterales.
- Mortality was 28% and relapse occurred in 7% of cases.
Conclusions:
- Enterococcal vascular graft infections are associated with comorbidities and intra-cavitary prostheses.
- These infections often occur early post-surgery and present as polymicrobial.
- The virulence of enterococci in these settings warrants careful consideration.
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