Risks for prolonged mechanical ventilation and reintubation after cervical malignant tumor surgery: a nested...

Area of Science:

• Oncology
• Neurosurgery
• Critical Care Medicine

Background:

• Malignant cervical tumors pose significant surgical challenges.
• Prolonged mechanical ventilation (PMV) and reintubation are critical postoperative complications.

Purpose of the Study:

• To determine the incidence and characteristics of PMV and reintubation in patients undergoing surgery for malignant cervical tumors.
• To identify independent risk factors associated with PMV and reintubation in this patient cohort.

Main Methods:

• Retrospective nested case-control study conducted from January 2014 to January 2020.
• Univariate and logistic regression analyses were employed to identify risk factors.
• Statistical significance was set at p < 0.05.

Main Results:

• Incidence rates for PMV and reintubation were 4.82% and 3.57%, respectively, in 560 patients.
• Independent risk factors for PMV included Karnofsky Performance Status < 50, operation duration ≥ 8 hours, and C4 nerve root tumor encasement.
• Longer operative duration and preoperative hypercapnia were independent risk factors for reintubation, leading to increased length of stay and 17.0% in-hospital mortality.

Conclusions:

• Identified specific risk factors for PMV and reintubation following malignant cervical tumor surgery.
• Highlights the need for meticulous patient assessment, early detection, and preventative strategies in this high-risk population.