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Updated: Jun 23, 2025

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Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
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[Cat-scratch disease, clinical features in adults]
Edwin A Rodríguez Arias1, Rossio G Ortuño Lobo1, Constanza Giardullo1
1Servicio de Clínica Médica, Hospital Nacional Profesor Alejandro Posadas, Buenos Aires, Argentina.
Medicina
|June 22, 2024
Summary
Cat-scratch disease (CSD), caused by Bartonella henselae, is often overlooked in adults. This study highlights its clinical presentation and outcomes in adult patients, emphasizing the need for greater awareness.
Area of Science:
- Infectious Diseases
- Bacteriology
- Epidemiology
Context:
- Cat-scratch disease (CSD) is primarily known as a pediatric illness, leading to under-recognition in adult populations.
- Bartonella henselae is the causative agent of CSD, with varied clinical manifestations.
- Limited data exists on the specific clinical features and outcomes of CSD in adults.
Purpose:
- To describe the clinical characteristics, treatment, and outcomes of CSD in adult patients.
- To enhance the understanding of CSD presentation in individuals over 15 years of age.
- To address the diagnostic challenges associated with CSD in adults.
Summary:
- A case-series study analyzed 30 adult patients diagnosed with CSD between 2016-2021.
- Peripheral lymphadenopathy was the most common symptom (90%), with a 33% complication rate.
- Most patients received antimicrobial therapy, and 83% had a favorable outcome.
Impact:
- This research contributes valuable data to the under-described clinical features of CSD in adults.
- Findings can aid clinicians in diagnosing and managing CSD in adult patients more effectively.
- Increased awareness of adult CSD may improve patient outcomes and reduce diagnostic delays.
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