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Related Experiment Video

Updated: May 1, 2026

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Synthesis of Multi-walled Carbon Nanotubes Modified with Silver Nanoparticles and Evaluation of Their Antibacterial Activities and Cytotoxic Properties

Published on: May 10, 2018

Single-atom nanozymes for antibacterial applications.

Siying Zhang¹, Weidong Ruan¹, Jingqi Guan¹

¹Institute of Physical Chemistry, College of Chemistry, Jilin University, 2519 Jiefang Road, Changchun 130021, PR China.

|June 22, 2024

Summary

Single-atom nanozymes (SAzymes) offer a promising alternative to antibiotics for combating bacteria. This review explores their catalytic properties and synergistic antibacterial effects with photothermal and sonodynamic therapies.

Keywords:

Antibacterial application Antibacterial mechanism Photothermal therapy Single-atom nanozyme Sonodynamic therapy

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Area of Science:

Biomaterials Science
Nanotechnology
Catalysis
Antimicrobial Research

Background:

Bacterial infections pose significant threats to human health and food safety.
Antibiotic resistance necessitates the development of novel antibacterial strategies.
Conventional antibiotics face challenges including resistance and side effects.

Purpose of the Study:

To review the antibacterial applications of single-atom nanozymes (SAzymes).
To discuss the catalytic properties of SAzymes relevant to antibacterial action.
To explore the synergistic potential of SAzymes with photothermal therapy (PTT) and sonodynamic therapy (SDT).

Main Methods:

Review of existing literature on SAzymes for antibacterial applications.
Analysis of SAzyme catalytic mechanisms, including active sites and coordination environments.
Investigation of carrier selection strategies for SAzyme delivery and efficacy.

Main Results:

SAzymes exhibit efficient bacterial elimination due to high atomic utilization and enzyme mimicry.
Catalytic properties can be tuned via active site engineering and carrier selection.
Synergistic effects with PTT and SDT enhance SAzyme antibacterial efficacy.

Conclusions:

SAzymes represent a potent alternative to conventional antibiotics.
Further research into SAzyme design and application is warranted.
SAzymes hold significant potential for addressing bacterial resistance and improving health outcomes.