Related Experiment Video
Updated: Jun 23, 2025

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Screening for women at risk of spontaneous preterm birth, including cervical incompetence
1Department of Obstetrics and Gynaecology, The Chinese University of Hong Kong, Hong Kong SAR China, China.
Insights
Preventing preterm birth is crucial for neonatal outcomes. Identifying modifiable risk factors, infections, and short cervix aids in developing effective, individualized prevention strategies.
Area of Science:
- Obstetrics and Gynecology
- Neonatal Care
- Perinatology
Background:
- Preterm birth presents a significant global health challenge with long-term neonatal consequences.
- Advances in neonatal care improve survival rates but highlight the need for effective prevention strategies.
- Current screening methods for preterm birth lack universal applicability.
Purpose of the Study:
- To summarize current evidence on preterm birth prevention.
- To discuss optimal clinical strategies for various high-risk scenarios.
- To provide guidance for preconceptional and antenatal risk factor identification.
Main Methods:
- Review of current scientific literature on preterm birth screening and prevention.
- Analysis of evidence for identifying modifiable risk factors.
- Discussion of clinical management strategies for specific patient groups.
Main Results:
- No single screening strategy is universally effective for preterm birth prevention.
- Identifying modifiable risk factors, genitourinary infections, and short cervical length are key screening components.
- Tailored approaches are necessary for managing conditions like cervical incompetence, prior preterm birth, and multiple gestations.
Conclusions:
- Effective preterm birth prevention requires individualized strategies based on identified risk factors.
- Early identification and management of risk factors are essential for improving neonatal outcomes.
- Further research into universal and targeted prevention methods is warranted.
Abstract:
Preterm births remain one of the biggest challenges in obstetrics worldwide. With the advancement of neonatal care, more premature neonates survive with long term consequences. Therefore, preventing or delaying preterm births starting from the preconceptional or antenatal periods are important. Among the numerous screening strategies described, not one can fit into all. Nonetheless, approaches including identifying women with modifiable risk factors for preterm births, genitourinary infections and short cervical length are the most useful. In this article, the current evidence is summarized and the best strategies for common clinical scenerios including cervical incompetence, history of second trimester loss or early preterm births, incidental short cervix and multiple pregnancy are discussed.

