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Improving equitable access for effective antibacterial: an ecosystem approach.

Jennifer Cohn1, Manica Balasegaram1, Hema Srinivasan2

  • 1Global Antibiotic Research and Development Partnership, Chemin Camille-Vidart 15, Geneva, Switzerland.

Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases
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Summary
This summary is machine-generated.

Equitable access to antibiotics is a global challenge. An ecosystem approach involving multiple stakeholders is needed to ensure sustainable supply and combat antimicrobial resistance.

Keywords:
AccessAntimicrobial resistanceHealth equityHealth systemsLow- and middle-income countries

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Area of Science:

  • Global Health
  • Antimicrobial Resistance
  • Health Equity

Background:

  • Antibiotics are crucial for modern healthcare, but equitable access is hindered by issues like limited evidence, pricing, and supply chain problems.
  • These challenges disproportionately impact low- and middle-income countries, worsening the global burden of antimicrobial resistance.
  • Existing incentives for antibiotic development are insufficient for achieving sustainable and equitable access.

Purpose of the Study:

  • To explore the complex dimensions of inequitable antibiotic access.
  • To propose a comprehensive framework and concrete interventions for improving global antibiotic access.

Main Methods:

  • Analysis of published literature.
  • Review of grey literature.
  • Incorporation of authors' expert knowledge.

Main Results:

  • Incentive-based approaches alone are inadequate for equitable antibiotic access.
  • An ecosystem approach involving diverse stakeholders and public-private partnerships is essential.
  • Interventions must span R&D, regulatory processes, procurement, and financing, tailored to specific contexts.

Conclusions:

  • Coordinated, cross-sectoral efforts are vital for equitable antibiotic access.
  • An ecosystem approach prioritizing public health needs can ensure sustainable antibiotic supply.
  • This strategy is crucial for safeguarding global healthcare against antimicrobial resistance.