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Updated: Jun 23, 2025

Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines
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Author Spotlight: Transmitochondrial Cybrid Generation Using Cancer Cell Lines

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CHCHD4 regulates the expression of mitochondrial genes that are essential for tumour cell growth

Luke W Thomas1, Jenna M Stephen1, Margaret Ashcroft1

  • 1Department of Medicine, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, United Kingdom.

Biochimica Et Biophysica Acta. Molecular Basis of Disease
|June 23, 2024
PubMed

Keywords:
CHCHD4CRISPR/Cas9 genome-wide deletion screenGene essentialityMitochondriaProteomicsSILAC analysis

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