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[A case of recurrent Campylobacter fetus meningitis, occurring two months after the initial infection was
Satoki Ito1, Takuya Tamura1, Yuji Ishihara1
1Department of Neurology, Ichinomiya Municipal Hospital.
Abstract:
A 43-year-old man was admitted to our department due to fever and headache. The cerebrospinal fluid analysis confirmed bacterial meningitis. Campylobacter species were isolated from blood cultures on the third day of admission. The patient was treated with meropenem (MEPM) and discharged on the 17th day. However, he experienced a recurrence of meningitis and was readmitted on the 68th day, initiating MEPM therapy. Campylobacter fetus was isolated from cerebrospinal fluid cultures on the 74th day. MEPM was continued until the 81st day, followed by one month of minocycline (MINO) therapy. The patient had an uneventful recovery without further recurrence. This case highlights the potential for recurrence of Campylobacter fetus meningitis approximately two months after the resolution of the initial infection. In addition to carbapenem therapy for at least two weeks, the adjunctive administration of MINO may be beneficial.
Insights
Recurrent bacterial meningitis caused by Campylobacter fetus can occur months after initial treatment. This case suggests carbapenem therapy plus minocycline may prevent relapses.
Area of Science:
- Infectious Diseases
- Neurology
- Microbiology
Background:
- Bacterial meningitis requires prompt diagnosis and treatment.
- Campylobacter species are an uncommon cause of meningitis.
Observation:
- A patient presented with recurrent meningitis due to Campylobacter fetus.
- Initial treatment with meropenem was followed by relapse.
Findings:
- Campylobacter fetus was isolated from cerebrospinal fluid during recurrence.
- Treatment with meropenem and subsequent minocycline led to recovery.
Implications:
- Campylobacter fetus meningitis may have a relapsing course.
- Prolonged carbapenem therapy and adjunctive minocycline may be beneficial for recurrent cases.
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