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Keyhole Aqueduct Syndrome.

Imad Zak1, Shahram Hadidchi2, Philip Ross3

  • 1Department of Radiology, Wayne State University-John D. Dingell VA Medical Center, 4646 John R Street, Detroit, MI, 48201, USA. izak@wayne.edu.

Neuroradiology
|June 23, 2024
PubMed
Summary
This summary is machine-generated.

Keyhole aqueduct syndrome, a rare neurodegenerative disorder, presents with a unique midline mesencephalic cleft. This case highlights the syndrome

Keywords:
AqueductKeyholeSyringomesencephalia

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Area of Science:

  • Neuroscience
  • Neurology
  • Ophthalmology

Background:

  • Keyhole aqueduct syndrome is a rare neurodegenerative disorder.
  • It is characterized by specific neuro-ophthalmologic, neuroimaging, and histopathological findings.

Observation:

  • A patient presented with vertical nystagmus, internuclear ophthalmoplegia, and progressive ataxia.
  • This patient exhibited a midline cleft connecting the cerebral aqueduct with the interpeduncular cistern.

Findings:

  • The observed midline cleft is a distinguishing feature of Keyhole aqueduct syndrome.
  • This finding aligns with previously reported imaging and histopathological characteristics.

Implications:

  • This case expands the understanding of Keyhole aqueduct syndrome.
  • Further research is needed to elucidate the full spectrum and pathogenesis of this rare condition.