Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Electron Microscope Tomography and Single-particle Reconstruction

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Comprehensive human locomotion and electromyography dataset: Gait120.

Scientific data·2025

Same author

Active Arm Swing During Running Improves Rotational Stability of the Upper Body and Metabolic Energy Efficiency.

Annals of biomedical engineering·2025

Same author

Dynamic Foot Pressure During Walking: A Potential Indicator of Bone Mineral Density.

The Journal of bone and joint surgery. American volume·2024

Same author

Effect of flatfoot correction on the ankle joint following lateral column lengthening: A radiographic evaluation.

PloS one·2023

Same author

Relationship between ankle varus moment during gait and radiographic measurements in patients with medial ankle osteoarthritis.

PloS one·2021

Same author

Inverse Relationship Between Radiographic Lateral Ankle Instability and Osteochondral Lesions of the Talus in Patients With Ankle Inversion Injuries.

Foot & ankle international·2019

Search research articles

Related Experiment Video

Updated: Jun 26, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

Fast digitally reconstructed radiograph generation using particle-based statistical shape and intensity model.

Jeongseok Oh¹, Seungbum Koo¹

¹Korea Advanced Institute of Science and Technology, Department of Mechanical Engineering, Daejeon, Republic of Korea.

Journal of Medical Imaging (Bellingham, Wash.)

|June 24, 2024

Summary

This summary is machine-generated.

A new particle-based method significantly speeds up the creation of digitally reconstructed radiographs (DRRs) and statistical shape and intensity models (SSIMs). This approach maintains high image quality, making it a faster alternative for 3D reconstruction and registration.

Keywords:

3D object representation digital radiography digitally reconstructed radiograph statistical shape and intensity model x-ray

More Related Videos

Three-Dimensional Particle Shape Analysis Using X-ray Computed Tomography: Experimental Procedure and Analysis Algorithms for Metal Powders

Three-Dimensional Particle Shape Analysis Using X-ray Computed Tomography: Experimental Procedure and Analysis Algorithms for Metal Powders

Published on: December 4, 2020

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

Related Experiment Videos

Last Updated: Jun 26, 2026

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Three-Dimensional Shape Modeling and Analysis of Brain Structures

Published on: November 14, 2019

Three-Dimensional Particle Shape Analysis Using X-ray Computed Tomography: Experimental Procedure and Analysis Algorithms for Metal Powders

Three-Dimensional Particle Shape Analysis Using X-ray Computed Tomography: Experimental Procedure and Analysis Algorithms for Metal Powders

Published on: December 4, 2020

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Digital Hybrid Model Preparation for Virtual Planning of Reconstructive Dentoalveolar Surgical Procedures

Published on: August 5, 2021

Area of Science:

Medical Imaging
Computational Geometry
Radiology

Background:

Statistical Shape and Intensity Models (SSIMs) and Digitally Reconstructed Radiographs (DRRs) are crucial for 2D-3D registration and skeletal reconstruction.
DRR computation is a time-consuming bottleneck in these processes.

Purpose of the Study:

To introduce a novel particle-based method for composing SSIMs and generating DRR images.
To analyze and compare the image quality of the proposed DRR generation scheme against existing methods.

Main Methods:

Developed a particle-based SSIM where particles represent object geometry and intensity.
DRR generation mimics ray tracing, calculating attenuation based on particle density and attenuation coefficients.
Compared the proposed method against tetrahedral-based SSIMs and CT projections using Mean Squared Error and Peak Signal-to-Noise Ratio (PSNR).

Main Results:

The particle-based method achieved a speed increase of approximately 600 times compared to tetrahedral-based SSIMs.
Attained a PSNR of 37.59 dB and a normalized pixel intensity root mean squared error of 0.0136.
Demonstrated high temporal performance and maintained image quality.

Conclusions:

The proposed SSIM and DRR generation procedure offers significant speed improvements.
Particle-based SSIMs are a viable representation for 3D volumes and effective for DRR generation.
This method presents a feasible and efficient approach for medical imaging applications.