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Published on: October 20, 2012
The Effect of Intra-socket Vitamin E Application on the Reduction in Postoperative Pain and Reduction in Incidence of
Mohamed Salah Mohamed Yousef1, Usama Abd El Raouf El Dakrory1, Yasser Nabil ELhadidi2
1Oral and Maxillofacial Surgery Department, Misr University for Science and Technology, 6th of October City, Egypt.
Introduction:
Blum defined dry socket as the presence of postoperative pain in and around the extraction site that worsens 1-3 days after the extraction.
Methods:
90 female patients seeking extraction of a single tooth in the lower posterior region were divided randomly into 45 patients who received vitamin E inside the socket after extraction (study group) and 45 patients who did not receive vitamin E after extraction (control group).
Results:
After 3 days, there was a decrease in pain levels in the study group compared to the control group. Only 7 patients out of 45 (16%) suffered from pain compared to 17 patients out of 45 (38%) in the control group. So, the improvement in pain was statistically significant P = 0.02. After 7 days, there was a decrease in wound healing levels in the study group compared to the control group. Only 8 patients out of 45 (17%) had poor wound healing compared to 7 patients out of 45 (16%) in the control group. However, the improvement in wound healing was not statistically significant P = 0.8.
Conclusion:
Based on the current results, we recommend the use of vitamin E as topical intra-socket medication in reducing the early postoperative pain.

