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Sydenham's chorea in a 16-year-old female from Bhutan: A case report
Tshering Penjor1, Thinley Dorji1, Sangay Wangchuk1
1Department of Internal Medicine Central Regional Referral Hospital Gelephu Bhutan.
Insights
Sydenham's chorea can be a key indicator of rheumatic fever, even without typical symptoms. Early echocardiography is crucial for detecting subclinical carditis to prevent rheumatic heart disease.
Area of Science:
- Pediatrics
- Cardiology
- Rheumatology
Background:
- Rheumatic heart disease (RHD) is preventable, yet remains a significant global health concern.
- Acute Rheumatic Fever (ARF) can present atypically, with Sydenham's chorea being a prominent manifestation, particularly in children.
- Clinical assessment alone may not detect carditis, necessitating advanced diagnostic tools.
Key Clinical Message:
Rheumatic heart disease is a preventable disease. Patients may not present with a typical history of sore throat and polyarthritis but may present with Sydenham's chorea. We should not rely completely on clinical findings to rule out carditis. Echocardiography should be done to rule out subclinical carditis.
Abstract:
Sydenham's chorea is a major manifestation of rheumatic fever. It occurs primarily in children and is seen rarely after the age of 20 years. We describe a 16-year-old girl who presented with purposeless involuntary movements of her upper and lower limbs. Laboratory blood reports showed raised erythrocyte sedimentation rate and anti-streptolysin O. 2D Doppler Echocardiography confirmed subclinical carditis, thickened mitral and aortic valve with mild mitral regurgitation. She was managed as Acute Rheumatic Fever with oral Phenoxymethyl penicillin and Carbamazepine. At the latest follow-up interviewing the caregiver, the patient had no sequelae. Early diagnosis is key to preventing late consequences of acute rheumatic fever and rheumatic heart disease. Sydenham's chorea is a rare presentation of acute rheumatic fever. The absence of clinical carditis does not rule out carditis.
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