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Updated: Jun 23, 2025
Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
Does Age Influence the Functional Recovery after Infant Pyeloplasty?
Heera Tharanendran1, Lakshmi Sundararajan1, Ramesh Babu2
1Department of Pediatric Surgery, Kanchi Kamakoti Childs Trust Hospital, Chennai, Tamil Nadu, India.
Purpose:
The purpose was to study the correlation between age at surgery and functional recovery after infant pyeloplasty.
Materials And Methods:
All infants who underwent pyeloplasty were analyzed retrospectively in this multicenter study. Anteroposterior diameter (APD) >2 cm, split renal function (SRF) <40%, and Society of Fetal Urology (SFU) grade 3-4 were surgical indications. Based on the age at pyeloplasty, they were divided into Group 1 (1-3 months) and Group 2 (4-12 months). APD and SRF were compared before and after surgery in both groups. The fractional recoverable function (post-SRF-pre-SRF)/(50-pre-SRF) ×100 was correlated with age.
Results:
Fifty-one infants underwent pyeloplasty (mean age: 1.6 months - Group 1 and 7.2 months - Group 2). The mean APD decreased from 3 cm to 1.2 cm in Group 1 while 2.8 cm to 2 cm in Group 2 (P = 0.001). The mean SRF increased from 32.28% to 42.81% in Group 1 while 31%-34.18% in Group 2. SRF recovery was significantly higher in Group 1 compared to Group 2 (P = 0.001). Regression analysis showed a weak negative correlation (r = -0.2792) between age at surgery and renal function improvement.
Conclusion:
Functional recovery after pyeloplasty is better when done earlier (1-3 months), as this gives the growing kidney the best opportunity to recover.
