Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A microcomputer-based quantitative morphometric analysis system for computing areas of amorphous patches.

L Berkwits, P M Iannaccone

    Computers and Biomedical Research, an International Journal
    |June 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Mechanics and spiral formation in the rat cornea.

    Biomechanics and modeling in mechanobiology·2014
    Same author

    GLI1 localization in the germinal epithelial cells alternates between cytoplasm and nucleus: upregulation in transgenic mice blocks spermatogenesis in pachytene.

    Biology of reproduction·2001
    Same author

    Nodal regulates trophoblast differentiation and placental development.

    Developmental biology·2001
    Same author

    Toxicogenomics: "the call of the wild chip".

    Environmental health perspectives·2001
    Same author

    The "new" genetics and mammalian cloning in environmental health research.

    Environmental health perspectives·2000
    Same author

    Nodal and bone morphogenetic protein 5 interact in murine mesoderm formation and implantation.

    Genesis (New York, N.Y. : 2000)·2000
    Same journal

    Wavelet domain nonlinear filtering for evoked potential signal enhancement.

    Computers and biomedical research, an international journal·2001
    Same journal

    Time-frequency analysis of the RT and RR variability to stratify hypertrophic cardiomyopathy patients.

    Computers and biomedical research, an international journal·2001
    Same journal

    Controlled auxotonic twitch in papillary muscle: a new computer-based control approach.

    Computers and biomedical research, an international journal·2001
    Same journal

    Controlling for chance agreement in the validation of medical expert systems with no gold standard: PNEUMON-IA and RENOIR revisited.

    Computers and biomedical research, an international journal·2001
    Same journal

    Artificial neural networks compared to factor analysis for low-dimensional classification of high-dimensional body fat topography data of healthy and diabetic subjects.

    Computers and biomedical research, an international journal·2000
    Same journal

    On the parallelization of linkmap from the LINKAGE/FASTLINK package.

    Computers and biomedical research, an international journal·2000
    See all related articles

    A new method analyzes irregular areas in histological sections using a digitizing tablet and microcomputer. This cost-effective system provides specialized output for mosaic tissues and data storage, demonstrated by liver patch analysis in chimeric rats.

    Area of Science:

    • Histology
    • Biotechnology
    • Computer-aided analysis

    Background:

    • Histological analysis often requires precise measurement of irregular areas.
    • Existing methods may lack efficiency or specialized output for complex tissue structures.
    • Mosaic tissues present unique challenges for quantitative analysis.

    Purpose of the Study:

    • To develop and present a novel method for the quantitative analysis of irregular areas in histological sections.
    • To demonstrate the utility of a computer-assisted system for histological data analysis.
    • To provide a cost-effective and efficient solution for analyzing complex tissue architectures.

    Main Methods:

    • Development of a computer-assisted analysis method utilizing a digitizing tablet and microcomputer.

    Related Experiment Videos

  • Implementation of specialized output formats suitable for mosaic tissue analysis.
  • Data storage on disk and plotter output for verification.

    • Main Results:

    • The developed system enables efficient analysis of irregular areas in histological samples.
    • Specialized output is generated, facilitating the study of mosaic tissue patterns.
    • The system was successfully applied to determine liver patch size in a novel chimeric rat model.

    Conclusions:

    • The described method offers an advantageous approach for analyzing irregular areas in histology.
    • The system's cost-effectiveness and specialized output make it valuable for mosaic tissue research.
    • This technique provides a robust tool for quantitative histological analysis, as evidenced by its application in chimeric rat studies.