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Published on: April 11, 2012
Case report: Multiple organ failure caused by Japanese spotted fever
Pei Zhou1, Yinhui Zhu1, Qian Cai1
1Department of Respiratory Medicine, The Third Hospital of Changsha, Hunan, 410015, China.
Abstract:
A 71-year-old male had disseminated multiple organ dysfunction syndrome (MODS). Following treatment with cefotaxime and piperacillin-tazobactam, his symptoms have worsened instead. Multiple organ failure caused by Japanese Spotted Fever (JSF) was diagnosed based on metagenomic next-generation sequencing (mNGS), we rapidly treated the patient with doxycycline. Thereafter, his symptoms gradually improved. In this report, we emphasized the importance of rapid microbial diagnostic tools and the early use of tetracyclines for the treatment of JSF.
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