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Updated: Jun 23, 2025

In Vesiculo Synthesis of Peptide Membrane Precursors for Autonomous Vesicle Growth
Published on: June 28, 2019
Neural-network-based solver for vesicle shapes predicted by the Helfrich model
Yousef Rohanizadegan1, Hong Li2, Jeff Z Y Chen1
1Department of Physics and Astronomy, University of Waterloo, Ontario, N2L3G1, Canada. yrohaniz@uwaterloo.ca.
Abstract:
That a three-dimensional vesicle morphology can be modeled by an artificial neural network is proposed and demonstrated. In the phase-field representation, the Helfrich bending energy of a membrane is equivalently cast into field-based energy, which enables a more direct representation of a deformable, three-dimensional membrane surface. The core of our method is incorporating recent machine-learning techniques to perform the required energy minimization. The versatile ability of the method, to compute axisymmetric and nonsymmetric shapes, is discussed.
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