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The Expert Panel for Cosmetic Ingredient Safety reaffirms that Sodium Dehydroacetate and Dehydroacetic Acid are safe for cosmetic use. This conclusion is based on repeated safety assessments conducted since 1985.

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Area of Science:

  • Cosmetic Science
  • Toxicology
  • Dermatology

Background:

  • The Expert Panel for Cosmetic Ingredient Safety (Panel) initially assessed Sodium Dehydroacetate and Dehydroacetic Acid in 1985.
  • Previous reviews in 2003 reaffirmed the safety conclusion.
  • The Panel's assessments focus on safety in current cosmetic product formulations and usage concentrations.

Purpose of the Study:

  • To conduct a re-review of the safety of Sodium Dehydroacetate and Dehydroacetic Acid.
  • To evaluate updated data on usage frequency and concentration.
  • To consider any new relevant safety information that has become available.

Main Methods:

  • Review of historical safety assessments from 1985 and 2006.
  • Analysis of updated cosmetic ingredient usage data from 2023.
  • Evaluation of newly published safety and toxicological studies.

Main Results:

  • The Panel reaffirmed the original conclusion that Sodium Dehydroacetate and Dehydroacetic Acid are safe as used in cosmetics.
  • Updated data on usage and safety did not alter the prior safety determination.
  • The ingredient's safety profile remains consistent across multiple reviews.

Conclusions:

  • Sodium Dehydroacetate and Dehydroacetic Acid are considered safe for use in cosmetic products.
  • The Panel's conclusion has been consistently upheld through multiple comprehensive safety reviews.
  • No new safety concerns were identified that would warrant a change in the established safety assessment.