Synthesis and antibacterial activity of 3-(2-arylvinylen)-2-isoxazolines

3-[2-(5-Nitro-2-furyl)vinylen]-2-isoxazoline (VIII) and 3-nitro-, 3-amino- and 3-acylaminostyryl-2-isoxazolines have been synthesized and tested for antibacterial activity. Compound (VIII) showed potent antibacterial activity in vitro against several strains of S. aureus and E. coli (two to eight times more active than furazolidone). None of the styryl derivatives exhibited significant activity.