Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cancer Survival Analysis01:21

Cancer Survival Analysis

342
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
342
  1. Home
  3. Research Domains
  5. Biomedical And Clinical Sciences
  7. Oncology And Carcinogenesis
  9. Predictive And Prognostic Markers
  11. Does Long-term Surveillance Imaging Improve Survival In Patients Treated For Head And Neck Squamous Cell Carcinoma? A Systematic Review Of The Current Evidence

Does Long-Term Surveillance Imaging Improve Survival in Patients Treated for Head and Neck Squamous Cell Carcinoma? A Systematic Review of the Current Evidence

Pattana Wangaryattawanich1, Yoshimi Anzai2, Carolyn Mead-Harvey3

  • 1From the Department of Radiology (P.W.), University of Washington School of Medicine, Seattle, Washington.

AJNR. American Journal of Neuroradiology
|June 24, 2024

Related Experiment Videos

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

11.5K
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

9.8K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.6K

View abstract on PubMed

Summary
This summary is machine-generated.

Long-term surveillance imaging after head and neck cancer treatment lacks standardized protocols and shows conflicting survival benefits. More high-quality research is needed to establish optimal imaging strategies for these patients.

Area of Science:

  • Oncology
  • Radiology
  • Medical Imaging

Background:

  • Current guidelines lack standardized long-term surveillance imaging protocols for head and neck squamous cell carcinoma (HNSCC) post-treatment.
  • Existing recommendations for surveillance imaging typically do not extend beyond six months due to ongoing debates on optimal strategies and efficacy.

Approach:

  • A systematic review was conducted to evaluate the impact of long-term surveillance imaging (beyond six months) on survival in HNSCC patients.
  • Searches were performed across major databases (PubMed, EMBASE, Scopus, Cochrane, Web of Science) for English literature published between 2003 and 2024.
  • Two retrospective studies meeting inclusion criteria were qualitatively assessed for bias and impact on survival.

Key Points:

  • No randomized prospective controlled trials were identified; only two retrospective studies with moderate risk of bias were included.

Related Experiment Videos

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
07:29

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment

Published on: April 22, 2019

11.5K
Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma
06:11

Therapy Testing in a Spheroid-based 3D Cell Culture Model for Head and Neck Squamous Cell Carcinoma

Published on: April 20, 2018

9.8K
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

3.6K
  • The included studies featured heterogeneous patient populations, variable risk profiles, and diverse imaging surveillance protocols.
  • Conflicting results were reported: one study suggested a survival benefit with FDG-PET/CT for advanced HNSCC, while the other found no survival benefit.

    • Conclusions:

    • Limited and heterogeneous retrospective data prevent definitive conclusions regarding long-term surveillance imaging's impact on HNSCC survival.
    • Insufficient high-quality evidence exists, highlighting the need for standardized definitions, protocols, and prospective multicenter registries to assess outcomes.