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Published on: November 3, 2023
Fifteen-minute consultation: a guide to paediatric major haemorrhage
Spyridon Karageorgos1,2, Dennis Ren2,3, Melanie Ranaweera2
1Aghia Sophia Children's Hospital, Athens, Greece.
Insights
Major hemorrhage protocols (MHPs) guide rapid blood product delivery in pediatric trauma, the second leading cause of death. This review synthesizes evidence-based management principles for pediatric major hemorrhage.
Area of Science:
- Pediatric Emergency Medicine
- Trauma Surgery
- Hemorrhagic Shock Management
Background:
- Major trauma significantly impacts pediatric morbidity and mortality.
- Severe hemorrhage is a leading cause of death in pediatric trauma patients.
- Current pediatric Major Hemorrhage Protocols (MHPs) often rely on adult data extrapolation.
Purpose of the Study:
- To provide an evidence-based synthesis of management principles for pediatric major hemorrhage.
- To address the challenges of applying adult MHP data to pediatric populations.
- To highlight the importance of multidisciplinary collaboration in managing pediatric major hemorrhage.
Main Methods:
- Review of existing literature and guidelines on pediatric major hemorrhage management.
- Synthesis of evidence-based principles for rapid blood product availability.
- Discussion of physiological differences between pediatric and adult responses to hemorrhage.
Main Results:
- Pediatric MHPs require careful consideration of age-specific physiological responses and injury mechanisms.
- Effective MHP implementation necessitates robust training, communication, and multidisciplinary teamwork.
- Rapid identification and management of severe hemorrhage are critical in pediatric trauma.
Conclusions:
- Evidence-based management of pediatric major hemorrhage is crucial for improving outcomes.
- Tailoring protocols to pediatric physiology, distinct from adult protocols, is essential.
- Successful management hinges on coordinated efforts from a multidisciplinary team.
Abstract:
Major trauma is a principal cause of morbidity and mortality in children. Severe haemorrhage is the second-leading cause of death in paediatric trauma, preceded by traumatic brain injury. Major haemorrhage protocols (MHPs), also known as 'code red' and 'massive transfusion protocols', are used to make large volumes of blood products rapidly available. Most recommendations for paediatric MHPs are extrapolated from adult data because of a lack of large, high-quality, prospective paediatric studies. However, applying adult data in a paediatric context requires caution due to differences in injury mechanisms and physiological responses between adults and children. Since major haemorrhage is a high-acuity low-occurrence event, MHP requires effective training, collaboration and communication among a large multidisciplinary team.In this 15-minute consultation, we provide an evidence-based synthesis of the management principles of paediatric major haemorrhage.
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