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Author Spotlight: Self-Assessment Protocol for Predicting Psoriatic Arthritis in Psoriasis Patients
Published on: March 1, 2024
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Association between psoriasis and asthma: a systematic review and bidirectional meta-analysis
Doudou Wu1, Xiangnan Zhou2, Fan Wu1
1Department of Integrative Traditional Chinese and Western Medicine, Beijing University of Chinese Medicine, Beijing, China.
BMC Pulmonary Medicine
|June 24, 2024
Summary
Psoriasis patients have a 48% higher risk of asthma, and asthma patients have a 33% higher risk of psoriasis. This bidirectional link highlights the need for increased awareness, especially for adolescents and those with severe psoriasis.
Area of Science:
- Dermatology and Pulmonology
- Epidemiology
- Systematic Reviews and Meta-Analyses
Background:
- Previous studies suggest a link between psoriasis and asthma, but the bidirectional relationship requires further exploration.
- The study addresses the need to fully understand the association between these two conditions.
Purpose of the Study:
- To investigate the bidirectional association between psoriasis and asthma.
- To quantify the risk of developing asthma in psoriasis patients and vice versa.
Main Methods:
- A comprehensive systematic literature search was conducted across PubMed, Embase, and the Cochrane Library up to October 2023.
- Meta-analysis of 16 observational studies involving 12,396,911 participants was performed using fixed or random effect models based on heterogeneity.
- Publication bias was assessed using funnel plots and Egger's test.
Main Results:
- Psoriasis patients demonstrated a significantly increased risk of developing asthma (OR = 1.48, 95% CI 1.28-1.68).
- Asthma patients also exhibited a significantly higher risk of developing psoriasis (OR = 1.33, 95% CI 1.23-1.44).
- Subgroup analyses indicated that study type, age, and psoriasis severity influenced asthma risk in psoriasis patients.
Conclusions:
- A significant bidirectional association exists between psoriasis and asthma.
- Clinicians should educate patients, particularly adolescents and those with moderate to severe psoriasis, about the elevated risk of developing the other condition.
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