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Groin pain aggravated in short term contracted by COVID-19 in THA patients: a case-crossover study
Hongjie Chen1, Peng Lai1, Haiming Lu1
1Department of Orthopedics, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Insights
Coronavirus disease 2019 (COVID-19) significantly increases the risk of groin pain aggravation in total hip arthroplasty (THA) patients. Longer hospital stays are also linked to this increased pain risk.
Area of Science:
- Orthopedic Surgery
- Infectious Diseases
- Pain Management
Background:
- Coronavirus disease 2019 (COVID-19) has caused global suffering.
- The impact of COVID-19 on groin pain in total hip arthroplasty (THA) patients was previously unclear.
- This study investigated the risk of groin pain aggravation in THA patients following COVID-19 infection.
Purpose of the Study:
- To evaluate the short-term risk of groin pain aggravation in total hip arthroplasty (THA) patients after COVID-19.
- To identify factors associated with increased groin pain in THA patients post-COVID-19.
Main Methods:
- A case-crossover study design was employed.
- 129 THA patients infected with COVID-19 between 2020 and 2022 were enrolled.
- A questionnaire assessed groin pain aggravation before and after SARS-CoV-2 infection, with multivariate analysis for associated factors.
Main Results:
- A significantly increased risk of inguinal pain aggravation was observed 8 weeks post-COVID-19 compared to 12 weeks pre-COVID-19 (RR, 9.5).
- Multivariate analysis identified a longer length of hospital stay as an independent factor associated with increased groin pain aggravation (OR, 1.26; p=0.027).
Conclusions:
- This study confirms a link between COVID-19 and exacerbated groin pain in THA patients.
- Extended hospital stay is identified as a potential contributing factor to this pain.
- Findings offer valuable insights into postoperative outcomes for THA patients affected by COVID-19.
Background:
The coronavirus disease 2019 (COVID-19) rapidly spreads worldwide and causes more suffering. The relation about the aggravation of inguinal pain and COVID-19 was unclear in patients with total hip arthroplasty (THA). This study aimed to evaluate the risk of groin pain aggravation in short-term THA patients after COVID-19.
Methods:
Between 2020 and 2022, 129 patients with THA who were affected COVID-19 were enrolled. A short-standardized questionnaire was administered during follow-up to inquire about the aggravation of groin ache before and after SARS-COV-2 affection. Furthermore, we evaluated the potential association between the presence of increased pain and various factors, including age, gender, body mass index, diagnosis, and length of hospital stay.
Results:
The case-crossover study revealed an increased risk of inguinal soreness aggravation when comparing 8 weeks after COVID-19 with 12 weeks before COVID-19 (Relative risk [RR], 9.5; 95% Confidence intervals [CI], 2.259-39.954). For COVID-19 positive patients, multivariate analysis showed length of stay was an independent factor significantly associated with increased risk of aggravation of groin pain (Odds ratio [OR], 1.26; 95%CI, 1.03-1.55, p = 0.027).
Conclusion:
This study confirms the association between COVID-19 and the exacerbation of soreness in the groin region in THA patients and extended length of stay is a possible contributing factor. This study expands the current literature by investigating the risk of aggravation of inguinal pain in patients with THA after COVID-19, providing valuable insights into postoperative outcomes in this specific population. Trial registration This retrospective study was approved by the Institutional Review Board of Shanghai general hospital (No.2023-264).
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