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Panacus: fast and exact pangenome growth and core size estimation

Luca Parmigiani1, Erik Garrison2, Jens Stoye1

  • 1Faculty of Technology and Center for Biotechnology (CeBiTec), Bielefeld University, Bielefeld, 33615, Germany.

Biorxiv : the Preprint Server for Biology
|June 25, 2024
PubMed
Abstract

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While every living organism has a genome of some kind (be it RNA, or DNA), there is considerable variation in the sizes of these blueprints. One major factor that impacts genome size is whether the organism is prokaryotic or eukaryotic. In prokaryotes, the genome contains little to no non-coding sequence, such that genes are tightly clustered in groups or operons sequentially along the chromosome. Conversely, the genes in eukaryotes are punctuated by long stretches of non-coding sequence.
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